Project PRIN 2022

Assessment of the missing link between Human Endogenous Retroviruses and gut microbiota-immunity axis in the colorectal cancer pathogenesis (HERMIA)

Date: 30/09/2025 – 29/09/2025

Principal investigator: Serena Delbue, PhD

Summary

Colorectal cancer (CRC) is a disease caused by multiple etiological factors, both environmental and genetic, affecting more than 1.8 million people worldwide. The project will investigate the ability of the Human Endogenous Retroviruses (HERVs) of exerting oncogenic potential, due to their (re)activation and translocation properties, in colon tissue, by themselves or in synergy with gut microbiota.