Services for companies
We carry out the following services for companies:
- In collaboration with a CRO, we perform in vitro ADME assays such as metabolism in human and animal hepatocytes, and permeability assays (in Caco-2 and MDCK)
- In vitro assays to evaluate the antiviral or neutralising activity of potential drugs (detection using plaque assay, TCID or genomic amplification methods) or surfaces with disinfecting properties (experiments according to the ISO standards
- Chemosensitivity assays for antimalarial activity against various strains and various stages of Plasmodium falciparum
- Chemosensitivity assays for anti-leishmaniasis activities against various species and stages (promastigote/amastigote) of Leishmania
- Immunomodulation assays: evaluation of cytokines/chemokines (ELISA), Nitric Oxide (Griess reagent), oxidative stress (DCF-DA)
- Angiogenesis models: endothelial cell proliferation, tube formation assay (Matrigel), scratch migration assay
- Erythroid differentiation for toxicity studies (K562 leukaemia line)
- Cytotoxicity/proliferation tests on different human and murine cell types (MTT, LDH tests)
- Antibacterial activity: evaluation of Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC)