{"id":1673,"date":"2024-09-11T13:07:08","date_gmt":"2024-09-11T11:07:08","guid":{"rendered":"https:\/\/parviruslab1.unimi.it\/?p=1673"},"modified":"2024-09-12T09:57:08","modified_gmt":"2024-09-12T07:57:08","slug":"progetto-prin-2022","status":"publish","type":"post","link":"https:\/\/parvirlab.unimi.it\/en\/2024\/09\/11\/progetto-prin-2022\/","title":{"rendered":"Project PRIN 2022"},"content":{"rendered":"\n<div class=\"wp-block-group minicard\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<figure class=\"wp-block-image size-medium is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"571\" height=\"600\" src=\"https:\/\/parviruslab1.unimi.it\/wp-content\/uploads\/sites\/118\/2024\/07\/Macrofago-infetto-1-571x600.jpg\" alt=\"\" class=\"wp-image-1190\" style=\"width:223px;height:auto\" srcset=\"https:\/\/parvirlab.unimi.it\/wp-content\/uploads\/sites\/118\/2024\/07\/Macrofago-infetto-1-571x600.jpg 571w, https:\/\/parvirlab.unimi.it\/wp-content\/uploads\/sites\/118\/2024\/07\/Macrofago-infetto-1-768x807.jpg 768w, https:\/\/parvirlab.unimi.it\/wp-content\/uploads\/sites\/118\/2024\/07\/Macrofago-infetto-1.jpg 829w\" sizes=\"(max-width: 571px) 100vw, 571px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><strong><em><strong><em>The role of proteIn foldiNg in proTozoan infEctions: unravelling the inteRACTtome of Leishmania molecular chaperones (INTERACT)<\/em><\/strong><\/em><strong><em> <\/em><\/strong><\/strong><\/h2>\n\n\n\n<p><strong>Date: <\/strong>28\/09\/2023 \u2013 27\/09\/2025<\/p>\n\n\n\n<p><strong>Principal investigator:<\/strong> Silvia Parapini, PhD<\/p>\n<\/div><\/div>\n\n\n\n<div style=\"height:32px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div style=\"height:0px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading has-medium-font-size\">Summary<\/h3>\n\n\n\n<p>Leishmaniasis, an endemic zoonosis in the Mediterranean basin, is closely related to the ability of parasites of the <em>Leishmania<\/em> genus to undergo morphological transformations in response to rapid environmental changes during the human stages of their life cycle. INTERACT project aims at identifying and comparing the interactome of Hsp90 in <em>Leishmania<\/em> human amastigote stages and in its promastigote vector stage. Collected data could be used as enabling tools to expand the insufficient arsenal of protein targets to develop novel and selective antiprotozoal agents, to counteract the harming phenomenon of drug resistance.<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The role of proteIn foldiNg in proTozoan infEctions: unravelling the inteRACTtome of Leishmania molecular chaperones (INTERACT) Date: 28\/09\/2023 \u2013 27\/09\/2025 Principal investigator: Silvia Parapini, PhD Summary Leishmaniasis, an endemic zoonosis in the Mediterranean basin, is closely related to the ability of parasites of the Leishmania genus to undergo morphological transformations in response to rapid environmental [&hellip;]<\/p>\n","protected":false},"author":319,"featured_media":1191,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[41],"tags":[],"class_list":["post-1673","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-funded-projects"],"acf":[],"_links":{"self":[{"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/posts\/1673"}],"collection":[{"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/users\/319"}],"replies":[{"embeddable":true,"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/comments?post=1673"}],"version-history":[{"count":4,"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/posts\/1673\/revisions"}],"predecessor-version":[{"id":1732,"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/posts\/1673\/revisions\/1732"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/media\/1191"}],"wp:attachment":[{"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/media?parent=1673"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/categories?post=1673"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/tags?post=1673"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}