{"id":1380,"date":"2024-07-26T23:43:11","date_gmt":"2024-07-26T21:43:11","guid":{"rendered":"https:\/\/parviruslab1.unimi.it\/?p=1380"},"modified":"2024-09-12T09:56:51","modified_gmt":"2024-09-12T07:56:51","slug":"project-funded-by-the-medical-research-council-uk-2022","status":"publish","type":"post","link":"https:\/\/parvirlab.unimi.it\/en\/2024\/07\/26\/project-funded-by-the-medical-research-council-uk-2022\/","title":{"rendered":"Project funded by the Medical Research Council (UK) 2022"},"content":{"rendered":"\n<div class=\"wp-block-group minicard\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<figure class=\"wp-block-image size-medium is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"443\" height=\"600\" src=\"https:\/\/parviruslab1.unimi.it\/wp-content\/uploads\/sites\/118\/2024\/07\/Poster-plasmodium-falciparum-443x600.jpg\" alt=\"\" class=\"wp-image-1198\" style=\"width:223px;height:auto\" srcset=\"https:\/\/parvirlab.unimi.it\/wp-content\/uploads\/sites\/118\/2024\/07\/Poster-plasmodium-falciparum-443x600.jpg 443w, https:\/\/parvirlab.unimi.it\/wp-content\/uploads\/sites\/118\/2024\/07\/Poster-plasmodium-falciparum-768x1040.jpg 768w, https:\/\/parvirlab.unimi.it\/wp-content\/uploads\/sites\/118\/2024\/07\/Poster-plasmodium-falciparum-756x1024.jpg 756w, https:\/\/parvirlab.unimi.it\/wp-content\/uploads\/sites\/118\/2024\/07\/Poster-plasmodium-falciparum.jpg 945w\" sizes=\"(max-width: 443px) 100vw, 443px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><strong><strong><em><strong><em>Lead optimisation of a series of antimalarial Plasmepsin IX\/X beta-hydroxyethylamine based inhibitors<\/em><\/strong><\/em><\/strong><\/strong><\/h2>\n\n\n\n<p><strong>Date:<\/strong> 01\/02\/2024 \u2013 31\/01\/2026<\/p>\n\n\n\n<p><strong>Principal investigator:<\/strong> Paul O\u2019Neill (University of Liverpool)<\/p>\n\n\n\n<p><strong>Participants:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Nicoletta Basilico, Silvia Parapini, Sarah D\u2019Alessandro (University of Milan)<\/li>\n\n\n\n<li>Neil Berry, David Hong (University of Liverpool)<\/li>\n\n\n\n<li>Giancarlo Biagini, Stephen Ward (Liverpool School of Tropical Medicine)<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading has-medium-font-size\">Summary<\/h3>\n\n\n\n<p>Malaria is an infectious disease caused by parasites of the genus <em>Plasmodium<\/em>. The disease results in over 600.000 deaths annually, primarily among children under the age of five in Africa. The project aims to find new antimalarial molecules, capable of inhibiting two enzymes, Plasmepsin IX and X, crucial for the survival of the parasite. It is a multinational effort involving researchers from the UK (University of Liverpool, Imperial College, Liverpool School of Tropical Medicine), Italy (University of Milan), and Switzerland (MMV, University of Geneva).<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Lead optimisation of a series of antimalarial Plasmepsin IX\/X beta-hydroxyethylamine based inhibitors Date: 01\/02\/2024 \u2013 31\/01\/2026 Principal investigator: Paul O\u2019Neill (University of Liverpool) Participants: Summary Malaria is an infectious disease caused by parasites of the genus Plasmodium. The disease results in over 600.000 deaths annually, primarily among children under the age of five in Africa. [&hellip;]<\/p>\n","protected":false},"author":319,"featured_media":1199,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[41],"tags":[],"class_list":["post-1380","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-funded-projects"],"acf":[],"_links":{"self":[{"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/posts\/1380"}],"collection":[{"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/users\/319"}],"replies":[{"embeddable":true,"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/comments?post=1380"}],"version-history":[{"count":8,"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/posts\/1380\/revisions"}],"predecessor-version":[{"id":1727,"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/posts\/1380\/revisions\/1727"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/media\/1199"}],"wp:attachment":[{"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/media?parent=1380"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/categories?post=1380"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/tags?post=1380"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}