{"id":1635,"date":"2024-07-16T13:00:09","date_gmt":"2024-07-16T11:00:09","guid":{"rendered":"https:\/\/parviruslab1.unimi.it\/?page_id=1635"},"modified":"2024-09-12T10:00:16","modified_gmt":"2024-09-12T08:00:16","slug":"linee_di_ricerca","status":"publish","type":"page","link":"https:\/\/parvirlab.unimi.it\/en\/research\/linee_di_ricerca\/","title":{"rendered":"Research areas"},"content":{"rendered":"\n

Our laboratory specializes in three main research areas:<\/p>\n\n\n

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\"Graph<\/figure><\/div>\n\n\n
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Pathology<\/mark><\/h3>\n\n\n\n

1. The role of oxygen in inflammation, innate immunity, and wound healing processes.<\/p>\n<\/div>\n\n\n\n

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Parasitolog<\/mark>y<\/h3>\n\n\n\n

2. Pathogenesis studies of severe malaria (cerebral malaria, severe anemia) caused by Plasmodium falciparum<\/em>.<\/p>\n\n\n\n

3. Host-parasite interaction studies, including research on the innate immune response to P. falciparum<\/em> and its products (hemozoin, HZ).<\/p>\n\n\n\n

4. Studies on the immunomodulatory activity of Leishmania<\/em> spp.<\/p>\n\n\n\n

5. Studies on the effect of co-infections on the pathogenesis of parasitic diseases and the development of neurological disorders (Alzheimer\u2019s disease).<\/p>\n\n\n\n

6. Search for compounds with antimalarial and antileishmanial activity, and studies on the mechanism of action of antimalarial drugs.<\/p>\n\n\n\n

7. Development of methods for the identification of new antiparasitic agents.<\/p>\n<\/div>\n\n\n\n

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Virolog<\/mark>y<\/h3>\n\n\n\n

8. Study of the pathogenesis of diseases associated with human Polyomaviruses.<\/p>\n\n\n\n

9. Study of viral replication\/reactivation in immunocompromised individuals.<\/p>\n\n\n\n

10. Study of the involvement of Human Endogenous Retroviruses (HERVs) in tumor pathologies.<\/p>\n\n\n\n

11. Development of molecular tests for virological diagnosis.<\/p>\n\n\n\n

12. SARS-CoV-2 and other respiratory viruses: clinical implications of infection. <\/p>\n\n\n\n

13. SARS-CoV-2 and other respiratory viruses: drug research.<\/p>\n\n\n\n

14. Creation of a strain library, currently including the following viruses: Human Polyomavirus JC and BK (JCPyV, BKPyV), Herpes Simplex Virus 1 (HSV-1), Varicella Zoster Virus (VZV), Influenza Virus, SARS-CoV-2, West Nile Virus (WNV), and Zika Virus. All viruses are available for in vitro pharmacological and neutralization testing.<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Ci occupiamo di virologia e parassitologia<\/p>\n","protected":false},"author":318,"featured_media":0,"parent":1561,"menu_order":7,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-1635","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/pages\/1635"}],"collection":[{"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/users\/318"}],"replies":[{"embeddable":true,"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/comments?post=1635"}],"version-history":[{"count":8,"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/pages\/1635\/revisions"}],"predecessor-version":[{"id":1731,"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/pages\/1635\/revisions\/1731"}],"up":[{"embeddable":true,"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/pages\/1561"}],"wp:attachment":[{"href":"https:\/\/parvirlab.unimi.it\/en\/wp-json\/wp\/v2\/media?parent=1635"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}